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. 2006 Dec 4;175(5):791–802. doi: 10.1083/jcb.200606017

Figure 1.

Figure 1.

Wnt11 induces local accumulation of Fz7 at the plasma membrane. (A–L) Coexpression of fz7-yfp in green and membrane marker lyn-cfp in red (60 pg mRNA each) in the animal pole assay (pregastrula-stage embryos, 5 hpf) in the absence (A–C) and presence (D–L) of 5 (D–F), 10 (G–I), or 20 pg (J–L) of wnt11 mRNA. Arrowheads mark Fz7 accumulation at the plasma membrane. (M) Ratio of Fz7-YFP accumulations at the plasma membrane/cell contact number (2D quantification; 70 cells total from seven embryos were used per condition). (N) Ratio of Fz7-YFP accumulation length/total cell contact length. Note that in control cells, Fz7-YFP accumulations were never seen (70 measurements total from six embryos were used per condition). Error bars represent the SEM. Asterisks demarcate statistically significant differences (P < 0.05). Bar, 10 μm.