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β4 sustains HGF-induced anchorage-independent growth through the recruitment of Shp2. Representative images and quantitation of soft agar assays in MDA-MB-231 cells displaying the artificial manipulation of β4 levels as shown in Fig. 2 E. Data are the means ± SEM (error bars) of two independent experiments performed in triplicate. **, P < 0.01 with respect to all other transfectants. WT, wild type. Bar, 400 μm.
