Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 May 7;177(3):413–424. doi: 10.1083/jcb.200701122

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2007, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — Kinetochore ultrastructure is altered in cells depleted of hSgo2 and Aurora B. EM images of thin sections of mitotic cells that were transfected with control (A), hSgo2 (B and C), and Aurora B (D) siRNAs. Insets show enlarged views of kinetochores indicated by the white and black arrows. (A) Normal kinetochores (n = 32) with discrete inner (small white arrow) and outer plates (large white arrow). (B) hSgo2-depleted kinetochores (n = 12) reveal an outer plate, but lack a discernable inner plate, and the subjacent chromatin appears undercondensed (bracket). (C) Example of a C-shaped kinetochore with a prominent fibrous corona. (D) Cells depleted of Aurora B (n = 24) exhibit C-shaped kinetochores.