Table 3.
Inhibition. Decreases in short circuit current (SCC) after inhibition with indometacin (40 μM), bumetanide (2.5 μM), ouabain (200 nM) and amiloride (100 μM).
| Compound | N, n | Median | Range | P value | Mean | SEM | |
| μA·cm-2 | μA·cm-2 | ||||||
| Controls | Indometacin | 14, 20 | 16.0 | 3.4–41.4 | 11.2 | 4.3 | |
| D-patients | Indometacin | 3, 7 | 8.6 | 6.6–17.4 | 0.112 | 7.7 | 2.5 |
| Controls | Bumetanide | 12, 18 | 19.0 | 3.6–57.0 | 20.0 | 3.8 | |
| D-patients | Bumetanide | 4, 8 | 18.9 | 9.6–38.5 | 0.475 | 20.2 | 4.5 |
| Controls | Ouabain | 20, 31 | 27.4 | 4.0–103.4 | 33.9 | 5.5 | |
| D-patients | Ouabain | 8, 12 | 22.0 | 2.8–34.0 | 0.394 | 20.6 | 3.3 |
| Controls | Amiloride | 16, 28 | 6.5 | 2.0–40.0 | 11.9 | 2.1 | |
| D-patients | Amiloride | 4, 15 | 8.0 | 1.6–27.4 | 0.475 | 8.8 | 1.9 |