Table 1.
Horizontal gene transfers from bacteria to chromalveolates
| 1 | 2 | 3 | 4 | 5 | 6 |
| Domain (Pfam) | Protein family [Function] | Accession number | Number unigenes | Best Hit | Phylogeny |
| MVIM | Predicted dehydrogenase | EF540335 | 7 | 1e-57 | Fig. 2 |
| WECE | Pyridoxal phosphate dependent aminotransferase [Cell envelope biogenesis, outer membrane] |
EF540335 EF540337 |
12 | 2e-100 | Fig. 2 |
| Epimerase | NAD dependent epimerase/dehydratase [Cell envelope biogenesis, outer membrane] | EF540339 | 2 | 1e-56 | Fig. 3 |
| CAS-like | Clavaminic acid synthetase [Biosynthesis of clavulanic acid] |
EF540323 EF540325 |
3 | 1e-53 | Fig. 4 |
| MQO | Malate-quinone oxidoreductase [Energy metabolism] |
EF540331 EF540333 |
2 | 1e-98 | Fig. 5 |
| NADP-IDH | Monomeric NADP(+)-dependent isocitrate dehydrogenase. [Energy metabolism] |
EF540327 EF540328 |
2 | 1e-162 | Fig. 6 |
| Fe-ADH | Iron-containing alcohol dehydrogenase [Energy metabolism] | EF540326 | 1 | 2e-97 | Additional file 1 |
| PutA | NAD-dependent aldehyde dehydrogenases [Energy metabolism] | EF540338 | 2 | 2e-120 | Additional file 1 |
| PBPb | Substrate-bound, membrane-associated, periplasmic binding protein [Substrate transport] | EF540334 | 1 | 2e-26 | Additional file 1 |
| SIR2 | Silent information regulator 2 [Gene silencing, DNA repair] | EF540336 | 2 | 5e-39 | Additional file 1 |
| AslA | Arylsulfatase A [Substrate transport] | EF540322 | 1 | 1e-70 | Additional file 1* |
| COG3129 | SAM-dependent methyltransferase | EF540332 | 1 | 1e-23 | Additional file 1* |
| ATS1 | Alpha-tubulin suppressor [Cell division and chromosome partitioning, cytoskeleton] | EF540324 | 5 | 8e-52 | Additional file 1* |
| PdxA | Pyridoxal phosphate biosynthetic protein PdxA [Amino acid metabolism] | EF540340 | 1 | 4e-54 | Additional file 1* |
| COG3618 | Metal-dependent hydrolase of the TIM-barrel fold | EF540329 | 2 | 1e-55 | Additional file 1* |
| COG3022 | Hypothetical [unknown] | EF540330 | 1 | 4e-26 | Additional file 1* |
1. The Pfam domain designation [29, 30]. 2. Confirmed or proposed function of the prokaryotic homologs is given. 3. GenBank accession number. 4. Numbers of unigenes encoding particular protein identified in the Karenia brevis EST data are given. Only one copy of gene was submitted into the GenBank. All gene copies can be found at [111]. 5. E-values for the best bacterial hit from the GenBank nonredundant database. 6. Phylogenetic trees for all proteins present in dinoflagellates and at least one other eukaryotic lineage (BLASTp e-value ≤ 10-10).
*The protein was found only in dinoflagellates and prokaryotes.