Table 2.
Characteristics of different thresholds for the body mass index (BMI), waist circumference and waist hip ratio (WHR), corresponding to a 30%, 40% and 50% screening of the population. Subjects aged 40 to 64 years who were not treated for diabetes. The D.E.S.I.R. Study.
| MEN | WOMEN | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| threshold | sensitivity | specificity | LR1 | (se+sp)/2 | threshold | sensitivity | specificity | LR | (se+sp)/2 | |
| screening with a blood test 30% of the population | ||||||||||
| BMI | 27 kg/m2 | 77 % | 69 % | 2.5 | 73 % | 26 kg/m2 | 77 % | 71 % | 2.6 | 74 % |
| Waist | 96 cm | 74 % | 71 % | 2.5 | 72 % | 83 cm | 82 % | 69 % | 2.6 | 75 % |
| WHR | 0.96 | 66 % | 70 % | 2.2 | 68 % | 0.83 | 77 % | 70 % | 2.5 | 73 % |
| screening with a blood test 40% of the population | ||||||||||
| BMI | 26 kg/m2 | 83 % | 57 % | 1.9 | 70 % | 25 kg/m2 | 86 % | 63 % | 2.4 | 75 % |
| Waist | 93 cm | 83 % | 59 % | 2.0 | 71 % | 80 cm | 86 % | 60 % | 2.2 | 73 % |
| WHR | 0.94 | 81 % | 59 % | 2.0 | 70 % | 0.81 | 77 % | 60 % | 1.9 | 68 % |
| screening with a blood test screening 50% of the population | ||||||||||
| BMI | 25 kg/m2 | 89 % | 44 % | 1.6 | 66 % | 24 kg/m2 | 86 % | 53 % | 1.8 | 70 % |
| Waist | 90 cm | 87 % | 47 % | 1.6 | 67 % | 77 cm | 86 % | 49 % | 1.7 | 68 % |
| WHR | 0.93 | 81 % | 53 % | 1.7 | 67 % | 0.79 | 86 % | 48 % | 1.7 | 67 % |
| optimal thresholds, maximizing the average of the sensitivity and specificity | ||||||||||
| BMI | 27 kg/m2 | 77 % | 69 % | 2.5 | 73 % | 25 kg/m2 | 86 % | 63 % | 2.4 | 75 % |
| Waist | 97 cm | 72 % | 74 % | 2.8 | 73 % | 85 cm | 77 % | 74 % | 3.0 | 76 % |
| WHR | 0.95 | 77 % | 65 % | 2.2 | 71 % | 0.83 | 77 % | 70 % | 2.5 | 73 % |
LR: likelihood ratio