Table 3.

Clinical and laboratory spectrum of thiazide-associated hypercalcemia among Olmsted County, Minnesota, residents, 1992-2001, overall and subset later found to have primary hyperparathyroidism

Characteristic	All patients mean ± SD, or n (%)	Primary Hyperparathyroidism subset mean ± SD, or n (%)
Female gender	68 (94.4)	19 (95.0)
Age at onset of hypercalcemia, yrs	63.9 ± 11.3	66.2 ± 11.2
Serum calcium prior to thiazide use, mg/dL	9.7 ± 0.4	9.7 ± 0.5
Maximum serum calcium on thiazides, mg/dL	10.7 ± 0.3	11.0 ± 0.4
Serum parathyroid hormone, pmol/L	4.8 ± 2.7	6.3 ± 4.4
Years from thiazide start to hypercalcemia	6.0 ± 7.2	7.3 ± 8.5
Reason for thiazide use
Hypertension	68 (94.4)	20 (100)
Edema	2 (2.8)	0 (0)
Hypercalciuria/nephrolithiasis	2 (2.8)	0 (0)