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. Author manuscript; available in PMC: 2008 Sep 15.
Published in final edited form as: Virology. 2007 May 16;366(1):212–225. doi: 10.1016/j.virol.2007.04.014

FIG. 1.

FIG. 1

The expression cassettes designed for expression of RVFV-specific antigen from SINV and VEEV replicons. (A) The schematic representation of SINV and VEEV replicons used in the study. The arrow indicates the position of the subgenomic promoter. (B) The hydrophobicity profile (Kyte-Doolitle) of the entire polyprotein encoded by the M segment of RVFV genome, and the fragments cloned into the subgenomic RNA of SINV replicon. The positions of signal peptides and transmembrane domains are indicated by black boxes. The spGn(opt) synthetic gene, encoding exactly the same protein as does spGn, is indicated in grey color. The starting and the last a.a. of each cassette are indicated.