Figure 4. The Probability of Developing Cancer, Defined as the Occurrence of a Cell with Any 20 Mutated Genes Out of 100.

Simulation results are displayed for three different population sizes (10⁹, solid lines; 10⁷, dashed lines; 10⁵, dotted lines), three different selection coefficients (10%, red lines; 1%, green lines; 0.1%, blue lines), and two different mutation rates (10⁻⁷, top; 10⁻⁵, bottom).