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. 2006 Mar;91(3):259–264. doi: 10.1136/adc.2004.068684

Table 1 Causes of intestinal failure.

Category Disorder
Short bowel syndrome Neonatal period
Gastroschisis
Necrotising enterocolitis
Small bowel atresia
Malrotation with volvulus
Total aganglionosis
Older children
Crohn's disease
Mesenteric infarction
Radiation enteritis
Tumours
Trauma
Motility disorders Hirschprung's disease
Hollow visceral myopathy
Neuronal intestinal dysplasia
Megacystis‐microcolon‐hypoperistalsis syndrome
Abnormalities of interstitial cells of Cajal
Mucosal disorders Primary epithelial abnormalities
Microvillous inclusion disease
Tufting enteropathy (primary epithelial dysplasia)
Congenital disorders of glycosylation
Immune mediated
Underlying immunodeficiency states, e.g. severe combined immunodeficiency, pan‐hypogammaglobulinaemia
Autoimmune
 Autoimmune enteropathy with nephropathy (AIE‐75/harmonin antibody)
Unclassified autoimmune enteropathy
 Syndromic intractable diarrhoea