Table 1 Timing and results of biopsies in infants presenting with infantile liver disease.
Patient | Age at bone marrow biopsy | Bone marrow aspirate result | Age at initial liver biopsy | Liver biopsy result | Age at repeat liver biopsy | Liver biopsy result | ||
---|---|---|---|---|---|---|---|---|
(mth) | LM | (mth) | LM | EM | PBD | (mth) | LM | |
1 | 1.5 | − | 1.5 | − | s | yes | 5.5 | + |
2 | 1.5 | − | 1.5 | − | s | no | x | x |
3 | 1.5 | + | 1.5 | − | s | yes | x | x |
4 | 3 | + | 3 | − | s | no | x | x |
5 | 4 | − | 4 | − | s | no | x | x |
6 | 10 | + | x | x | x | x | x | x |
7 | 11 | + | 11 | + | x | no | x | x |
8 | 16 | − | 1.5 | − | n | yes | 16 | + |
9 | 17 | + | 4 | − | x | no | 17 | + |
10 | 29 | + | 29 | + | x | x | x | x |
11 | 47 | + | 1.5 | − | n | yes | 24 | poor quality |
Details of patients listed according to their age at the time of bone marrow aspirate.
+, presence of storage cells; −, no storage cells seen; s, suggestive; n, non‐suggestive; x, not done.
LM, light microscopy; EM, electron microscopy; PBD, paucity of bile ducts.