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. 2007 Nov 8;117(12):3833–3845. doi: 10.1172/JCI32567

Figure 5. TNF-α and TNFR1 on APCs are required for optimal activation in response to inflammatory cytokines.

Figure 5

Bone marrow–derived macrophages were generated from mice of the indicated genotypes and treated for 20 hours with IFN-γ, TNF-α, or LPS. The levels of CD40 and CD86 expression were then evaluated by flow cytometry. Data are representative of 2 independent experiments.