Table 2.
Expression of inflammatory infiltrates in MS lesions and controls
| Case no. (Age/Sex) | CD3 | CD4 | CD8 | CD68 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Lesion (no.) | Lesion type | Perivascular | Parenchymal | Perivascular | Parenchymal | Perivascular | Parenchymal | Perivascular | Parenchymal | |
| 1 (38/F) | Frontal plaques (3) | Acute | + | + | + | + | + | + | +++ | +++ |
| NLWM | ++ | + | ++ | + | + | + | ++ | ++ | ||
| NLGM | + | - | ++ | + | + | - | ++ | - | ||
| 2 (61/F) | Occipital plaques (3) | Ch. active | + | + | - | - | + | - | ++ | ++ |
| NLWM | ++ | + | ++ | + | + | - | ++ | +++ | ||
| NLGM | +++ | ++ | + | - | + | + | ++ | + | ||
| 3 (62/M) | Parietal plaques (3) | Ch. active | ++ | + | ND | ND | - | - | +++ | ++ |
| NLWM | ++ | + | ND | ND | + | - | ++ | +++ | ||
| NLGM | ++ | + | + | + | ++ | - | ++ | + | ||
| 4 (51/F) | Frontal plaques (3) | Acute | ++ | + | ND | ND | + | - | +++ | +++ |
| NLWM | ++ | + | + | + | - | - | +++ | ++ | ||
| NLGM | ND | ND | + | - | ND | ND | ++ | + | ||
| 5 (60/M) | Occipital plaques (3) | Acute | +++ | + | ND | ND | + | - | ++ | + |
| NLWM | + | + | ++ | - | ++ | + | +++ | ++ | ||
| NLGM | + | + | + | - | - | - | ++ | + | ||
| 6 (51,F) | Occipital plaques (3) | Acute | + | - | + | - | + | - | ++ | ++ |
| NLWM | ++ | - | + | - | ++ | - | ++ | +++ | ||
| NLGM | ++ | + | ++ | - | + | - | ++ | ++ | ||
| 7 (30, F) | Frontal plaques (3) | Acute | ++ | + | + | - | + | - | +++ | ++ |
| NLGM | + | - | + | - | ++ | - | ++ | + | ||
| 8-12 | Normal (4) | Control WM | - | - | - | - | - | - | - | - |
| Control GM | - | - | - | - | - | - | - | - | ||
F, female; M, male; NLWM, non-lesion white matter; NLGM, non-lesion gray matter. -, negative; +, slightly positive; ++, positive; +++, highly positive; ND, not determined; Ch. active, chronic active