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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Ultrasound Med Biol. 2007 Apr;33(4):584–590. doi: 10.1016/j.ultrasmedbio.2006.10.004

Figure 1.

Figure 1

MR image showing the signal intensity increase due to localized BBBD produced by focused ultrasound pulses combined with Definity® in the rabbit brain at four locations. The signal intensity increase was created from contrast-enhanced T1-weighted images normalized to a T1-weighted image acquired before baseline. The peak rarefactional pressure amplitude (estimated in brain) was 0.2, 1.1, 0.4, and 0.8 MPa for locations 1-4, respectively.