. 2007 Jul 5;367(2):307–323. doi: 10.1016/j.virol.2007.05.041

Table 1.

Characteristics of immunodeficient mice

Name	Strain (Stock number)^a	Description	Reference
C57BL/6	B6 (#000664)	Parental strain (wild type)	(Waterston et al., 2002)
αβ TCR KO	B6.129P2-Tcrb^tm1Mom/J (#002118)	Disruption of T-cell receptor beta (Tcrb) chain	(Mombaerts et al., 1992)
αβ TCR KO		Deficient in αβ T cells (CD4⁺CD8⁺ cells ~ 6% of wild-type)	(Mombaerts et al., 1992)
γδ TCR KO	B6.129P2-Tcrd^tm1Mom/J (#002120)	Disruption of T-cell receptor delta (Tcrd) chain	(Itohara et al., 1993)
γδ TCR KO	B6.129P2-Tcrd^tm1Mom/J (#002120)	Deficient in γδ T cells (all adult lymphoid and epithelial organs)	(Itohara et al., 1993)
μMT KO	B6.129S2-Igh-6^tm1Cgn/J (#002288)	Disruption in immunoglobulin heavy chain-6 (Igh-6, heavy chain of IgM)	(Kitamura et al., 1991)
μMT KO	B6.129S2-Igh-6^tm1Cgn/J (#002288)	Deficient in mature B cells	(Kitamura et al., 1991)
IFN-γR KO	129-Ifngr1^tm1Agt/J (#002702)	Disruption of interferon gamma receptor 1 (Ifngr1)	(Huang et al., 1993)
IFN-γR KO	129-Ifngr1^tm1Agt/J (#002702)	Deficient in functional IFN-γR	(Huang et al., 1993)

All mice were purchased from Jackson Laboratories (Bar Harbor, Maine).

Immunodeficient (knockout, KO) mice were developed on the C57BL/6 (B6) background, which are described as parental (wild type, WT) in the text.