Table 3.
Summary of phenotypes observed in cells overexpressing YOR193w, PEX25, or PEX11
| Strain | Overexpressed gene | Normal peroxisomes | Large peroxisomes | Small peroxisomes | Clustered peroxisomes |
|---|---|---|---|---|---|
| yor193Δ | - | ++a | +++ | ||
| yor193Δ | YOR193w | ++++ | + | ||
| yor193Δ | PEX25 | ++++ | + | ||
| yor193Δ | PEX11 | ++++ | + | ||
| pex25Δ | - | ++ | +++ | ||
| pex25Δ | YOR193w | + | + | +++ | |
| pex25Δ | PEX25 | ++++ | + | ||
| pex25Δ | PEX11 | + | +++ | + | |
| pex11Δ | - | + | ++++ | ||
| pex11Δ | YOR193w | + | ++++ | ||
| pex11Δ | PEX25 | ++ | +++ | ||
| pex11Δ | PEX11 | + | + | +++ | |
| yor193Δ/pex25Δ | - | + | ++++ | ||
| yor193Δ/pex25Δ | YOR193w | ++ | + | + | + |
| yor193Δ/pex25Δ | PEX25 | ++ | ++ | + | |
| yor193Δ/pex25Δ | PEX11 | +++ | ++ | ||
| yor193Δ/pex11Δ | - | +++++ | |||
| yor193Δ/pex11Δ | YOR193w | +++++ | |||
| yor193Δ/pex11Δ | PEX25 | +++++ | |||
| yor193Δ/pex11Δ | PEX11 | + | ++ | ++ | |
| pex25Δ/pex11Δ | - | +++++ | |||
| pex25Δ/pex11Δ | YOR193w | + | ++++ | ||
| pex25Δ/pex11Δ | PEX25 | +++++ | |||
| pex25Δ/pex11Δ | PEX11 | +++ | ++ | ||
| BY4742 | - | +++++ | |||
| BY4742 | YOR193w | +++ | ++ | ||
| BY4742 | PEX25 | ++ | + | ++ | |
| BY4742 | PEX11 | +++ | ++ |
a
The (+) symbol denotes the presence of a particular peroxisomal phenotype. Increased numbers of (+) symbols denote increased prevalence of a particular peroxisomal morphological phenotype. The absence of a (+) symbol denotes the absence of a particular peroxisomal morphological phenotype.