Figure 3.

TI-VAMP and L1 are coexpressed in growing axonal tracts in the developing rat brain. Expression of L1 and TI-VAMP in the developing brain. E15 and E19 embryos were serially sectioned in the sagittal plane and labeled for TI-VAMP and L1 (right). In all four examples shown there is a high degree of colocalization. (A) Olfactory nerve branching out in the olfactory epithelium. (B and C) Trigeminal ganglion and nerve root. In B, the trigeminal nerve ganglion contains TI-VAMP–labeled neurons. Their labeled axons are seen to converge toward the brainstem, and in C, trigeminal nerve branches fan out toward the facial vibrissae (left). (D) In the forebrain, TI-VAMP–labeled axon tracts are observed that correspond to corticofugal pathways and to cortical afferent pathways (bar, 100 μm).