Skip to main content
British Journal of Cancer logoLink to British Journal of Cancer
. 1961 Sep;15(3):515–530. doi: 10.1038/bjc.1961.62

Tumours of Many Sites Induced by Injection of Chemical Carcinogens into Newborn Mice, A Sensitive Test for Carcinogenesis: The Implications for Certain Immunological Theories

F J C Roe, K E K Rowson, M H Salaman
PMCID: PMC2071152  PMID: 14493235

Full text

PDF
520

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAUER W. H., BYRNE J. J. Induced tumors of the parotid gland. Cancer Res. 1950 Dec;10(12):755–761. [PubMed] [Google Scholar]
  2. BOCK F. G., KING D. W. A study of the sensitivity of the mouse forestomach toward certain polycyclic hydrocarbons. J Natl Cancer Inst. 1959 Oct;23:833–839. [PubMed] [Google Scholar]
  3. BOUTWELL R. K., BOSCH D. K. The carcinogenicity of creosote oil: its role in the induction of skin tumors in mice. Cancer Res. 1958 Nov;18(10):1171–1175. [PubMed] [Google Scholar]
  4. FIORE-DONATI L., CHIECO-BIANCHI L., DE BENEDICTIS G., MAIORANO G. Leukaemogenesis by urethan in new-born Swiss mice. Nature. 1961 Apr 15;190:278–279. doi: 10.1038/190278a0. [DOI] [PubMed] [Google Scholar]
  5. HAM A. W., McCULLOCH E. A., AXELRAD A. A., SIMINOVITCH L., HOWATSON A. F. The histopathological sequence in viral carcinogenesis in the hamster kidney. J Natl Cancer Inst. 1960 May;24:1113–1129. [PubMed] [Google Scholar]
  6. HEIDELBERGER C., WEISS S. M. The distribution of radioactivity in mice following administration of 3,4-benzpyrene-5-C14 and 1,2,5,6-dibenzanthracene-9,10-C14. Cancer Res. 1951 Nov;11(11):885–891. [PubMed] [Google Scholar]
  7. HORNING E. S. The influence of unilateral nephrectomy on the development of stilboestrol-induced renal tumours in the male hamster. Br J Cancer. 1954 Dec;8(4):627–634. doi: 10.1038/bjc.1954.68. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. KELLY M. G., O'GARA R. W. Induction of tumors in newborn mice with dibenz[a, h]anthracene and 3-methylcholanthrene. J Natl Cancer Inst. 1961 Mar;26:651–679. [PubMed] [Google Scholar]
  9. KOLETSKY S., GUSTAFSON G. E. Whole body radiation as a carcinogenic agent. Cancer Res. 1955 Feb;15(2):100–104. [PubMed] [Google Scholar]
  10. LAW L. W., DUNN T. B., BOYLE P. J. Neoplasms in the C3H strain and in F1 hybrid mice of two crosses following introduction of extracts and filtrates of leukemic tissues. J Natl Cancer Inst. 1955 Oct;16(2):495–539. [PubMed] [Google Scholar]
  11. LUCKE B. Kidney carcinoma in the leopard frog: a virus tumor. Ann N Y Acad Sci. 1952 Jul 10;54(6):1093–1109. doi: 10.1111/j.1749-6632.1952.tb39981.x. [DOI] [PubMed] [Google Scholar]
  12. NEUKOMM S. Un test sensible et ultra-rapide du pouvoir cancérigène de certaines substances chimiques. Oncologia. 1957;10(2):107–119. [PubMed] [Google Scholar]
  13. PIETRA G., SPENCER K., SHUBIK P. Response of newly born mice to a chemical carcinogen. Nature. 1959 Jun 13;183(4676):1689–1689. doi: 10.1038/1831689a0. [DOI] [PubMed] [Google Scholar]
  14. ROE F. J., PEIRCE W. E. Tumor promotion by citrus oils: tumors of the skin and urethral orifice in mice. J Natl Cancer Inst. 1960 Jun;24:1389–1403. [PubMed] [Google Scholar]
  15. ROE F. J., SALAMAN M. H., COHEN J. Incomplete carcinogens in cigarette smoke condensate: tumour-promotion by a phenolic fraction. Br J Cancer. 1959 Dec;13:623–633. doi: 10.1038/bjc.1959.68. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. ROGERS S. Comparative carcinogenesis. Arch Pathol. 1960 Dec;70:661–674. [PubMed] [Google Scholar]
  17. SHIMKIN M. B. Pulmonary tumors in experimental animals. Adv Cancer Res. 1955;3:223–267. doi: 10.1016/s0065-230x(08)60921-5. [DOI] [PubMed] [Google Scholar]
  18. SMITH R. T., BRIDGES R. A. Immunological unresponsiveness in rabbits produced by neonatal injection of defined antigens. J Exp Med. 1958 Aug 1;108(2):227–250. doi: 10.1084/jem.108.2.227. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. STANTON M. F., STEWART S. E., EDDY B. E., BLACKWELL R. H. Oncogenic effect of tissue-culture preparations of polyoma virus on fetal mice. J Natl Cancer Inst. 1959 Dec;23:1441–1475. [PubMed] [Google Scholar]
  20. SUNTZEFF V., COWDRY E. V., CRONINGER A. Microscopic visualization of the degeneration of sebaceous glands caused by carcinogens. Cancer Res. 1955 Nov;15(10):637–640. [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES