Table 3.
Incubation time [h] | Parent compound | Active compound | Inactive metabolite | |
Beclomethasone | 2 | 60.9 ± 7.0 | 35.7 ± 6.4 | 3.4 ± 0.8 |
Dipropionate1 | 6 | 19.1 ± 8.3 | 53.5 ± 4.3 | 27.3 ± 4.7 |
24 | - | 8.4 ± 5.3 | 91.6 ± 5.3 | |
Ciclesonide | 2 | 94.9 ± 1.3 | 5.1 ± 1.3 | - |
6 | 83.2 ± 5.5 | 16.8 ± 5.5 | - | |
24 | 37.4 ± 7.8 | 62.6 ± 7.8 | - |
Data are presented as mean ± standard deviation (n = 9).
No metabolites of Bud and FP were detected in medium.
1The active compound of BDP may be overestimated as inactive 21-BMP may be included.