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Effects of swainsonine on sensitivity to 5-FU and mRNA expression of 5-FU-related enzymes. mRNA expression of TS, OPRT and UP following swainsonine treatment of L0 (open column) and L0-1000 (closed column) measured by real-time RT-PCR. Data represent the ratio relative to the parental L0 cell without swainsonine. Each column represents the mean with S.D. of 4 measurements.
