Table 4.
Structural features of cDNA/protein sequences of the dual clip-domain serine proteinases
| HP12 | HP24 | PAP-2 | HP15 | HP23 | PAP-3 | PPAE | |
|---|---|---|---|---|---|---|---|
| cDNA length, bp | 1428 | 1416 | 2299 | 1376 | 2177 | 1381 | 1447 |
| open reading frame, bp | 1368 | 1359 | 1326 | 1326 | 1332 | 1284 | 1326 |
| protein length, residues | 455 | 452 | 441 | 441 | 443 | 427 | 441 |
| signal peptidase cutting site | G19|Q | G19|Q | G19|Q | G17|Q | G17|E | G19|Q | A21|Q |
| isoelectric point of mature protein | 5.27 | 5.47 | 6.02 | 5.03 | 7.40 | 6.53 | 9.10 |
| calculated Mr of mature protein | 47,780 | 48,146 | 45,797 | 46,811 | 47,395 | 44,174 | 45,637 |
| N-linked glycosylation site | 3 | 1 | 2 | 6 | 5 | 2 | 2 |
| O-linked glycosylation site | 1 | 2 | 1 | 1 | 1 | 3 | 3 |