Figure 2. Ratios of Cytophilic to Noncytophilic Anti-MSP3 Responses Found Among Protected and Nonprotected Individuals of Dielmo.

The mean ratios of (IgG1 + IgG3) to (IgG2+ IgG4+ IgM) antibody responses (i.e., the cytophilic to noncytophilic [C:NC] ratios) were calculated for protected (open circles) and unprotected individuals (closed circles) within each age group. Error bars indicate the SD calculated for each age group. The number of individuals within each group is indicated in parentheses. A protected person is defined as an individual in whom no malaria attack was recorded during the first year of follow-up.