TABLE 2.
Variable | Baseline control group | Baseline sildenafil group | 4 ± 2 months after sildenafil | Δ% after sildenafil | P value¶ |
---|---|---|---|---|---|
peak V̇O2, L • min−1 | 0.79 ± 0.18 | 0.84 ± 0.11 | 0.91 ± 0.10 | 8.8 | 0.074 |
peak V̇O2, ml •min−1•kg−1 | 11.34 ± 0.57 | 11.41 ± 1.15 | 12.38 ± 0.94 | 8.8 | 0.050 |
AT, L • min−1 | 0.61 ± 0.04 | 0.61 ± 0.06 | 0.67 ± 0.05 | 4.1 | NS |
V̇E/V̇CO2 | 50 ± 2.9 | 49 ± 2.3 | 43 ± 2.2 | −14.9 | 0.009 |
peak WR, watts | 57 ± 5.4 | 60 ± 10 | 68 ± 8.9 | 13.7 | 0.050 |
PetCO2, mmHg | 27 ± 1.5 | 26 ± 1.5 | 30 ± 1.9 | 10.4 | 0.006 |
rest HR | 81 ± 4.4 | 88 ± 1.9 | 87 ± 2.3 | −1.2 | NS |
peak HR, bpm | 136 ± 5.1 | 139 ± 5.0 | 139 ± 4.4 | 0.1 | NS |
peak O2 pulse, ml•min−1•beat−1 | 6.2 ± 0.4 | 6.1 ± 0.7 | 6.8 ± 0.8 | 10.0 | 0.014 |
Lowest SaO2, % | 92 ± 1.5 | 90 ± 2.3 | 90 ± 2.3 | 0.4 | NS |
peak RER | 1.16 ± 0.03 | 1.18 ± 0.03 | 1.21 ± 0.03 | 2.4 | NS |
values are ± SEM
post-sildenafil compared to baseline