Table 3.
Group of drugs | ATC | Guideline drugs | Mostly encountered non-guideline drugs in our study population | |
---|---|---|---|---|
HMG CoA reductase inhibitors | C10AA | C10AA01, C10AA03 | Simvastatin, Pravastatin | Fluvastatin, Rosuvastatin, Atorvastatin |
Drugs for acid-related diseasesa | A02 | A02A, A02BA | Antacids, H2-receptor antagonists | Proton pump inhibitors |
Antibacterials for systemic use | J01 | J01A, J01B | Tetracyclines, Amfenicoles | Quinolone antibacterials |
J01C except J01CR02 | Beta-lactam antibacterials except amoxicilline and enzyme inhibitor | Amoxiciline and enzyme inhibitor | ||
Cefalosporins | ||||
J01E | Sulfonamids and Trimethoprim | |||
J01F | Macrolides, lincosamides, streptogramins | |||
J01X | Other antibacterials (e.g. Fusidic acid) | |||
Antidepressants | N06A | N06AA09, N06AA02 | Amitryptiline, Imipramine | Maprotiline, Clomipramine, Fluoxetine |
N06AA10, N06AB08 | Nortriptyline, Fluvoxamine | Citalopram, Trazodone, Venlafaxine, Mirtazapin | ||
N06AB05, N06AB06 | Paroxetine, Sertraline | |||
Benzodiazepine derivatives and related drugsb | N05BA | N05CD07, N05CF02 | Temazepam, Zolpidem | Triazolam, Lormetazepam, Flunitrazepam, Loprazolam, Clobazam, Bromazepam, Lorazepam, Oxazepam, Chloordiazepoxide, Alprazolam, Zopiclone |
N05CD | N05BA01 | Diazepam | ||
N05CF | ||||
Drugs for obstructive airway diseases | R03 | R03AC | Selective beta-2-adrenoreceptor agonists | Adrenergis for systemic use, Theophylline, |
Montelukast | ||||
R03BA, R03BB | Glucocorticoids, Anticholinergics | |||
R03BC01 | Cromoglicic acid | |||
Oral blood glucose lowering drugs | A10B | A10BB | Sulfonamides, urea derivatives | Repaglinide, Thiazolidinediones |
A10BA02, A10BF01 | Metformin, Acarbose |
aDrugs of first choice according to the corresponding NHG standard were only suitable for patients without use of NSAIDs. Therefore, for the index of adherence of the antacids, special DU90% segments had to be calculated for all PTAMs, with the additional postulation that only first deliveries of selected GPs were included for those patients who had not had a prescription of a NSAID in the preceding 4 months.
bThe valid NHG standard for hypnotics dated from 1992 and was quite obsolete. To better meet the actual standards and recommendations, we labelled the guideline drugs, recommended by another commonly used standard [23].