Higher kf,4 reduces the Tau-to-Tail Ratio. Increased kf,4 gives sharper peaks, but longer tails from the peak, and a lower Tau-to-Tail Ratio compared to flatter transients with a higher ratio when kf,4 is decreased. Simulations were performed with the equations as in Table 3 and the parameters and initial conditions as in Table 4. Additionally, ts = 100 s, Ls = 0.100 μM, and kf,4 was varied as depicted in the legend.