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Effect of enhancer fragments on MGMT minimal promoter activity as determined by CAT reporter assays. A204 Mer+ cells (shaded columns) and TK6 Mer− cells (solid columns) were transiently transfected with the indicated CAT reporter gene constructs (described in Fig. 1). Promoter activities are expressed relative to that of pCAT/MP containing the minimal promoter without an enhancer. Values represent the mean ± SD from three or more experiments.
