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. Author manuscript; available in PMC: 2007 Nov 9.
Published in final edited form as: Neuroscience. 2000;96(1):231–236. doi: 10.1016/s0306-4522(99)00408-x

Fig. 4.

Fig. 4

Repulsion of olfactory bulb axons by Slit. A–C show different views of the same co-culture with control HEK cells laid on top of the telencephalon. D–F show different views of the same co-culture with Slit expressing cells laid on top of the telencephalon. (A) A bright-field view of the olfactory bulb–telencephalon co-culture. Control cells were laid on top of the telencephalon and DiI was inserted into the olfactory bulb. OB indicates the olfactory bulb and Tel indicates the telencephalon. (B) A fluorescent view of the same co-culture as that shown in A; note that axons from the olfactory bulb projected into the telencephalon. (C) A superimposition of A and B. (D) A bright-field view of the olfactory bulb–telencephalon co-culture. Slit expressing cells were laid on top of the telencephalon. (E) A fluorescent view of the same co-culture as that shown in D; note that axons from the olfactory bulb turned away from the telencephalon. (F) A superimposition of D and E.