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. Author manuscript; available in PMC: 2007 Nov 9.
Published in final edited form as: Drug Discov Today. 2007 Feb 7;12(5-6):241–248. doi: 10.1016/j.drudis.2007.01.003

FIGURE 1.

FIGURE 1

Three modes of action of T. T might act directly through ARs, be converted to DHT by 5α-reductase before binding to ARs, and be aromatized to estrogen and act through the ER.