Table 5.
Detailed description of 24 true positive findings in patients operated on for spine tumors
| True positive cases | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient | Region | Pathology | Surgery | Duration (h) | IOM modalities | IOM-baseline | IOM-changes | Neurological deterioration | Duration | Recovery | |
| T.J., m, 55 years | e | L4-S2 | Carcinoma metastasis | Decompression, complete tumorexcision | 4.8 | cmEP, ncEP, in situ stimulation, BCR | Pathological cmEP and ncEP | Progressive alteration of all cmEP leg right | Deterioration of pre-existing radiculopathy L4&5 right | Exitus letalis after 2 months | No |
| E.D., f, 50 years | e | L3&4 | Carcinoma metastasis | Complete tumorcorpectomy ventral, fusion dorsal | 6.5 | csEP, cmEP, smEP, ncEP, nsEP, cont EMG | All available | Progressive deterioration of cmEP and smEP left leg | Radiculopathy L4&5 left | 5 months | Exitus letalis after 8 months |
| S.F., m, 59 years | e | L3 | Carcinoma metastasis | Complete tumorexcision and fusion dorsal | 4.2 | csEP, cmEP, nsEP | All available | deterioration of cmEP | Proximal weakness of legs | 2 days | complete |
| T.W., m, 56 years | e | C0-C3 | Hemangiopericytoma, recurrence | Decompression of myelon, partial tumorresection | 9.3 | csEP, cmEP, ncEP, in situ stimulation | All available | Alteration of cmEP trapecius muscle left | Mild accessory nerve paresis | 4 days | complete |
| Z.N., m, 67 years | e | L1-S1 | lipomatosis | Decompression and complete excision | 4 | csEP, cmEP, smEP, nsEP | All available | Loss of ncEP peroneal nerve left | Sensible radiculopathy S1 left | 2 weeks | complete |
| B.M., m, 44 years | e | L4-lumbosacral plexus | liposarcoma | Complete excision from dorsal | 4.3 | cmEP, ncEP, in situ stimulation, BCR | All available | Loss of cmEP TA&AH left, loss of ncEP PN&TN left | Ischiadic palsy left | 12 h | complete |
| S.S., f, 33 years | id-em | L2-S3 | ependymoma | Complete resection from dorsal | 7 | cmEP, in situ stimulation, ncEP, | All available | Deterioration of cmEP VM left | Quadriceps-paresis left | 1 day | complete |
| K.S., f, 26 years | id-em | S2-S5 | gangliopericytoma | Complete resection from dorsal | 7 | cmEP, smEP, ncEP, in situ stimulation, BCR | All available | Deterioration of cmEP PL left | Mild radiculopathy L5 left | 1 day | complete |
| E.P., m, 72 years | id-em | L3 | neurinoma | Complete excision from dorsal | 2.8 | cmEP, ncEP | All available | Deterioration of PN and FN sensory EP left | Mild radiculopathy L4 left | 2 days | complete |
| S.R., f, 56 years | im | C0-T1 | Congenital tumor with ACM I and Syrinx | Decompression dorsal | 3.8 | csEP, cmEP, ncEP | All available | Deterioration of ncEP MN left | Numbness left arm | 1 hour | complete |
| C.Y., m, 43 years | im | L1-S2 | ependymoma | Excision complete from dorsal | 7.6 | csEP, cmEP, ssEP, nsEP, ncEP, in situ Stimulation, cont EMG, BCR | All available, but pathologic | alteration of cmEP leg right | Weakness right leg | 6 hours | complete |
| K.A., m, 36 years | im | L3-S1 | ependymoma | Complete excision from dorsal | 7.5 | cmEP, smEP, nsEP, BCR, | All available, but all pathologic | Alteration of cmEP left leg and loss of BCR right | Weakness left leg | 2 months | complete |
| D.M., m, 38 years | im | T10&11 | Lipofibroma | Partial excision from dorsal | 6 | csEP, cmEP, smEP, ssEP, nsEP, ncEP, in situ stimulation | All available, but pathologic | Alteration of cmEP TA and AH right>left | Radiculopathy L5 und S1 right > left | 6 months | Recovery to pre-existing deficits |
| F.N., f, 27 years | e | T1-T3 | Aneurysmatic cyst | Complete tumorvertebrectomy and fusion dorsal | 5 | csEP, cmEP, ncEP, nsEP, cont EMG | All available | Complete loss of all cmEP after columnotomy. | paraplegia | 4 hrs | Complete |
| F.M., f, 66 years | id-em | T12-L1 | Meningeoma recurrence | Complete tumorexcision from dorsal | 3.8 | csEP, smEP, nsEP, ncEP, in situ stimulation | All available | Deterioration of cmEP and ncEP left leg | Mild deterioration of pre-existing paraparesis | 2 weeks | Complete to pre-existing deficits |
| S.B., f, 48 years | id-em | T7&8 | Chronic leptomeningitis | Partial resection from dorsal | 3.3 | csEP, cmEP, ssEP, nsEP | All available | Deterioration of all motor and sensory EP | Mild deterioration of paraparesis | 3 weeks | complete |
| G.M., f, 54 years | id-em | C3-C5 | meningeoma | Complete resection from dorsal | 7.8 | csEP, cmEP, nsEP, ncEP | All available, but severly pathologic | Deterioration of sensory and motor EP left | Deterioration of pre-existing spasticity and ataxia | 3 months | complete |
| P.M., f, 53 years | im | C0-T2 | Congenital tumor with ACM I and Syrinx | Decompression C0-C2 | 4.5 | cmEP, ncEP | All available, but pathological | Deterioration of ncEP MN bds | Deterioration of ataxia | 3 weeks after ventriculoperitoneal shunt implantation | Recovery to pre-existent deficits |
| S.H., f, 22 years | im | C0-T4 | Congenital tumor with ACM I and Syrinx | Decompression from dorsal | 4.3 | csEP, cmEP, nsEP, ncEP | All available | Loss of ncEP MN left and alteration of ncEP TN left | Hemiataxia left | 1 month | complete |
| R.P., m, 51 years | im | C0-T12 | Congenital tumor with ACM I and Syrinx | Decompression dorsal (Shunt) | 2.8 | cmEP, ncEP | All available, but pathological | Deterioration of ncEP TN and MN left | Hemiataxia left | 3 months | complete |
| S.I., f, 80 years | im | C1-C5 | ependymoma | Complete excision from dorsal | 5.3 | csEP, cmEP, ssEP, nsEP, ncEP, cont EMG | All available, but strongly pathologic | Loss of ncEP MN and cmEP BR bilateral and cmEP ADM left | Sensomotor tetraparesis right > left | 6 months | Recovery to pre-existing deficits |
| S.E., f, 87 years | im | C5-T1 | ependymoma | Partial resection from dorsal | 5 | csEP, cmEP, smEP, ssEP, nsEP, ncEP | All available, but pathologic | Alteration of all motor EP | Mild increase of spasticity | 3 weeks | Recovery to pre-existing deficits |
| F.Pl., m, 56 years | im | C3-C5 | neurinoma | Complete resection from dorsal | 5 | csEP, cmEP, ncEP | All available, but pathologic | Loss of ncEP MN right, reduction of ncEP MN left | Increased ataxia right > left | 4 months | Recovery to pre-existing deficits |
| M.L., m, 44 years | id-em | S1-lumbosacral plexus | ganglioneuroma | Decompression and complete excision, dorsoventral | 12.3 | cmEP, ncEP, in situ stimulation | All available | Loss of BCR and BAR right, ncEP TN right | Partial sphincter palsy | 3 months | complete |