Table 1.
Map of P2 receptor proteins in striatum and substantia nigra
| Striatum | Substantia nigra | |
|---|---|---|
| P2X1 | +++ | +++ |
| P2X2 | +++ | +++ |
| P2X3 | ++ | ++ |
| P2X4 | +++ | +++ |
| P2X5 | + | +++ |
| P2X6 | + | ++ |
| P2X7 | ++ | ++ |
| P2X1 | + | ++ |
| P2X2 | +++ | +++ |
| P2X4 | +++ | +++ |
| P2X6 | + | +++ |
| P2X11 | – | – |
| P2X12 | +++ | +++ |
| P2X13 | – | – |
| P2X14 | – | +++ |
Relative abundance of all P2X and P2Y receptor proteins was analyzed by confocal immunofluorescence microscopy, as described in “Materials and methods”. The intensity of the specific immunostaining was scored as follow: – = not detected; + = just sufficient to evaluate presence and outline of positive cells; ++ = adequate to assess morphological features of cell bodies and/or cellular processes; +++ = very bright