Table 1.
Two-point LOD score results between the MCPH3 locus and chromosome 9 markers
LOD score at recombination fraction θ = | ||||||||
Marker | Genetic distance* | Physical distance** | 0.00 | 0.01 | 0.05 | 0.1 | 0.2 | 0.3 |
D9S1801 | 112.31 | 109425991 | - inf | -2.73 | -1.39 | -0.85 | -0.37 | -0.14 |
D9S930 | 117.84 | 114276019 | 1.28 | 1.25 | 1.14 | 1.00 | 0.71 | 0.43 |
D9S302 | 122.69 | N.A | 1.58 | 1.54 | 1.39 | 1.19 | 0.82 | 0.47 |
D9S737 | 124.75 | 118592918 | 1.58 | 1.54 | 1.39 | 1.19 | 0.82 | 0.47 |
D9S762 | 126.40 | 120135547 | 1.58 | 1.54 | 1.39 | 1.19 | 0.82 | 0.47 |
D9S934 | 129.82 | 120135477 | 1.58 | 1.54 | 1.39 | 1.19 | 0.82 | 0.47 |
D9S1682 | 130.73 | 124033005 | 1.58 | 1.54 | 1.39 | 1.19 | 0.82 | 0.47 |
D9S242 | 133.72 | 125908748 | 1.58 | 1.54 | 1.39 | 1.19 | 0.82 | 0.47 |
D9S1881 | 141.5 | 126019246 | 0.96 | 0.95 | 0.89 | 0.79 | 0.57 | 0.33 |
D9S1847 | 147.72 | 134426754 | - inf | -2.16 | -0.89 | -0.45 | -0.13 | -0.04 |
*-Cumulative sex-averaged Kosambi genetic map distances (cM) from the Rutgers combined linkage-physical map of the human genome [31].
**-Sequences-based physical map distances in bases according to NCBI Build 36.1 of the human reference sequence [32].