(A) In vitro interaction between BPV-1 E6 and paxillin. GST–paxillin fusion protein (19) and GST protein were incubated with 35S-labeled, in vitro-translated BPV-1 E6, and bound E6 proteins were analyzed by SDS/PAGE and autoradiography. (B) Interaction between paxillin and HPV E6 proteins. HPV 16, 11, and 6 E6 proteins were 35S-labeled by in vitro translation and incubated with GST–paxillin, and bound E6 proteins were analyzed by SDS/PAGE and autoradiography.