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. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Dev Biol. 2006 Nov 21;303(1):391–404. doi: 10.1016/j.ydbio.2006.11.025

Figure 4. Msx1 expression is down regulated in the Meckel’s cartilage and mandible bone of Tgfbr2fl/fl;Wnt1-Cre mice.

Figure 4

(A–D) In situ hybridization of Msx1 mRNA within Meckel’s cartilage and the osteogenic front of the mandible bone (arrowhead) in control and Tgfbr2fl/fl;Wnt1-Cre mice at E13.5 and E14.5. (*) indicates Msx1 expression in A&C and no Msx1 expression in B&D. (E) Quantitative analysis of Msx1 mRNA expression by real time quantitative RT-PCR in Meckel’s cartilage at E13.5. Asterisks indicate statistical significance (p<0.01). Scale bar: 200μm in A–D