. 2007 Aug 17;73(19):6066–6071. doi: 10.1128/AEM.00654-07

TABLE 2.

Toxicity, resistance ratios, and interactions of Mtx-2 toxin with B. sphaericus and Cry11Aa and Cyt1Aa from B. thuringiensis subsp. israelensis against susceptible and insecticide-resistant C. quinquefasciatus larvae

Toxin(s) assayed	Mosquito colony	LC₅₀ (μg/ml) (fiducial limits) or relevant result	LC₉₅ (μg/ml) (fiducial limits)	Resistance ratio at:		SF at:
Toxin(s) assayed	Mosquito colony	LC₅₀ (μg/ml) (fiducial limits) or relevant result	LC₉₅ (μg/ml) (fiducial limits)	LC₅₀	LC₉₅	LC₅₀	LC₉₅
Mtx-2	Syn-P	4.13 (2.36-7.20)	347.9 (102-1216)	1.0	1.0	NA^a	NA
	BS-R	3.77 (2.26-6.27)	105.0 (35.9-320)	0.9	0.3	NA	NA
	Cq11A	49.6 (31.9-77.6)	702.7 (251.4-2053)	12.0	2.0	NA	NA
B. sphaericus	Syn-P	0.0330 (0.0188-0.0594)	0.825 (0.203-3.01)	1.0	1.0	NA	NA
	BS-R	17% mortality at 1,000 μg/ml		>1,000	NA	NA	NA
Cry11Aa	Syn-P	1.14 (0.452-2.89)	33.5 (6.96-163)	1.0	1.0	NA	NA
	Cq11A	1,181 (487-6,563)	223,893 (25,642-17.5 × 10⁶)	1,035	6,683	NA	NA
Cyt1Aa	Syn-P	14.1 (10.5-18.2)	504 (336-854)	1.0	1.0	NA	NA
	BS-R	27.8 (14.8-52.2)	674 (189-2432)	1.9	1.4	NA	NA
B. sphaericus + Mtx-2 (3:1)	Syn-P	0.00406 (0.00337-0.00490)	0.0828 (0.0564-0.134)	1.0	1.0	10.8	13.2
	BS-R	0.102 (0.0913-0.113)	0.298 (0.237-0.383)	25.1	3.5	147	1409
Mtx-2 + Cyt1Aa (1:1)	Syn-P	2.83 (2.12-3.78)	78.8 (45.7-142)	1.0	1.0	2.3	5.2
	BS-R	5.81 (4.94-6.83)	70.6 (52.8-99.9)	2.1	0.9	1.1	2.6
B. sphaericus + Mtx-2 +	Syn-P	0.0637 (0.0444-0.0915)	0.453 (0.234-0.895)	1.0	1.0	0.6	2.3
Cyt1Aa (8:1:1)	BS-R	0.755 (0.666-0.856)	3.56 (2.89-4.69)	11.9	7.9	44.0	255
B. sphaericus + Mtx-1 +	Syn-P	0.00730 (0.00618-0.00862)	0.0800 (0.0595-0.115)	1.0	1.0	5.6	12.3
Mtx-2 (8:1:1)	BS-R	0.195 (0.137-0.278)	0.920 (0.486-1.77)	26.7	11.5	12.4	23.1
Cry11Aa + Mtx-2 (3:1)	Syn-P	0.140 (0.0430-0.454)	2.02 (0.440-9.43)	1.0	1.0	9.9	21.8
	Cq11A	6.82 (1.82-25.4)	4,642 (64.3-347,492)	48.7	2,298	25.8	0.6

NA, not applicable.