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. 2007 Aug 17;73(19):6066–6071. doi: 10.1128/AEM.00654-07

TABLE 2.

Toxicity, resistance ratios, and interactions of Mtx-2 toxin with B. sphaericus and Cry11Aa and Cyt1Aa from B. thuringiensis subsp. israelensis against susceptible and insecticide-resistant C. quinquefasciatus larvae

Toxin(s) assayed Mosquito colony LC50 (μg/ml) (fiducial limits) or relevant result LC95 (μg/ml) (fiducial limits) Resistance ratio at:
SF at:
LC50 LC95 LC50 LC95
Mtx-2 Syn-P 4.13 (2.36-7.20) 347.9 (102-1216) 1.0 1.0 NAa NA
BS-R 3.77 (2.26-6.27) 105.0 (35.9-320) 0.9 0.3 NA NA
Cq11A 49.6 (31.9-77.6) 702.7 (251.4-2053) 12.0 2.0 NA NA
B. sphaericus Syn-P 0.0330 (0.0188-0.0594) 0.825 (0.203-3.01) 1.0 1.0 NA NA
BS-R 17% mortality at 1,000 μg/ml >1,000 NA NA NA
Cry11Aa Syn-P 1.14 (0.452-2.89) 33.5 (6.96-163) 1.0 1.0 NA NA
Cq11A 1,181 (487-6,563) 223,893 (25,642-17.5 × 106) 1,035 6,683 NA NA
Cyt1Aa Syn-P 14.1 (10.5-18.2) 504 (336-854) 1.0 1.0 NA NA
BS-R 27.8 (14.8-52.2) 674 (189-2432) 1.9 1.4 NA NA
B. sphaericus + Mtx-2 (3:1) Syn-P 0.00406 (0.00337-0.00490) 0.0828 (0.0564-0.134) 1.0 1.0 10.8 13.2
BS-R 0.102 (0.0913-0.113) 0.298 (0.237-0.383) 25.1 3.5 147 1409
Mtx-2 + Cyt1Aa (1:1) Syn-P 2.83 (2.12-3.78) 78.8 (45.7-142) 1.0 1.0 2.3 5.2
BS-R 5.81 (4.94-6.83) 70.6 (52.8-99.9) 2.1 0.9 1.1 2.6
B. sphaericus + Mtx-2 + Syn-P 0.0637 (0.0444-0.0915) 0.453 (0.234-0.895) 1.0 1.0 0.6 2.3
    Cyt1Aa (8:1:1) BS-R 0.755 (0.666-0.856) 3.56 (2.89-4.69) 11.9 7.9 44.0 255
B. sphaericus + Mtx-1 + Syn-P 0.00730 (0.00618-0.00862) 0.0800 (0.0595-0.115) 1.0 1.0 5.6 12.3
    Mtx-2 (8:1:1) BS-R 0.195 (0.137-0.278) 0.920 (0.486-1.77) 26.7 11.5 12.4 23.1
Cry11Aa + Mtx-2 (3:1) Syn-P 0.140 (0.0430-0.454) 2.02 (0.440-9.43) 1.0 1.0 9.9 21.8
Cq11A 6.82 (1.82-25.4) 4,642 (64.3-347,492) 48.7 2,298 25.8 0.6
a

NA, not applicable.