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Nck K229 disrupts migration of mesoderm cells. mRNA (0.1 ng) encoding nuclear-localized β-galactosidase plus 0.2 ng of either KALL control (A and C) or K229 (B and D) mRNA was injected into C1 blastomeres of 32-cell embryos. Embryos were fixed and stained with X-Gal at stage 12 (A and B) or stage 30 (C and D). (A and B) Embryos are positioned with animal pole at top and dorsal side to the right. (Bar = 100 μm.)
