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Alignment of NrpR domains of M. kandleri (Mk), M. maripaludis (Mm), and M. acetivorans (Ma). D1 and D2 differentiate between individual NrpR domains of M. maripaludis and M. acetivorans. Numbers at ends of rows indicate the amino acid positions based on the full-length NrpR sequences. Amino acids shown to be involved in 2OG sensing are underlined, and their mutations are indicated in brackets. Black, grey, and light grey represent 100%, 80%, and 60% conservation, respectively.
