Skip to main content
. Author manuscript; available in PMC: 2008 Aug 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2007 May 10;223(1):1–9. doi: 10.1016/j.taap.2007.04.014

Figure 3.

Figure 3

Bacterial clearance in IFN-γ-primed, particle-exposed, and S. pneumoniae-infected mice. Mice were primed with IFN-γ (I) or PBS (P) aerosols for 15 min., followed 3 hours later by intranasal exposure to PBS (P), TiO2 (T) or CAPs (C). 24 hours later mice were infected intranasally with S. pneumoniae (B). The lungs were harvested and bacterial load (CFU) was assessed 24 hours after infection, as described in Methods. Data represent the mean ± SEM of at least 3 independent experiments. * = p<0.05 compared to PPB and PTB groups. ** = p<0.001 compared to all other groups.