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. Author manuscript; available in PMC: 2008 Aug 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2007 May 10;223(1):1–9. doi: 10.1016/j.taap.2007.04.014

Table 1.

Genes activated 3, 6 or 24 hours after treatment with PBS (P) or IFN-γ (I) aerosol for 10 min., then intranasal PBS (P) or CAPs (C) 3 hours later.

Gene PP* PC IP IC Fold increase (IC/PP) Fold increase (IC/PC) Fold increase (IC/IP)
3 hours
MIP-1a 0.047 0.104 0.091 0.113 2.38 1.09 1.24
MIP-3b 0.038 0.062 0.041 0.083 2.19 1.34 2.02
MIP-1b 0.048 0.083 0.042 0.101 2.09 1.22 2.40
TECK 0.036 0.053 0.057 0.066 1.85 1.25 1.16
MDC 0.062 0.083 0.064 0.103 1.66 1.24 1.61
IL17B 0.094 0.126 0.126 0.146 1.56 1.16 1.16
6 hours
TARC 0.031 0.115 0.041 0.143 4.66 1.24 3.49
MCP-5 0.017 0.063 0.035 0.073 4.30 1.16 2.09
Lungkine 0.474 0.872 0.743 1.108 2.34 1.27 1.49
MIP-1g 0.052 0.104 0.073 0.111 2.11 1.07 1.52
IL-9 0.028 0.035 0.035 0.055 1.98 1.57 1.57
IL-1b 0.047 0.063 0.041 0.079 1.68 1.25 1.93
24 hours
IL-8Rb 0.015 0.024 0.025 0.047 3.07 1.96 1.88
MIP-1g 0.047 0.084 0.065 0.124 2.62 1.48 1.91
C-10 0.477 0.895 0.680 0.981 2.06 1.10 1.44
IL-1b 0.042 0.035 0.052 0.085 2.03 2.43 1.63
CCR-1 0.020 0.020 0.022 0.040 2.03 2.00 1.82
MIP-3a 0.084 0.123 0.127 0.142 1.69 1.15 1.12
CCR-2 0.056 0.045 0.061 0.084 1.5 1.87 1.38
*

Densitometric value Glossary: MIP1a = macrophage inflammatory protein 1 alpha; MIP3b = macrophage inflammatory protein 3 beta; MIP1b = macrophage inflammatory protein 1 beta; TECK = thymus-expressed chemokine; MDC = macrophage-derived chemokine; IL17B = interleukin 17B; TARC = thymus and activation regulated chemokine; MCP-5 = monocyte chemotactic protein 5; MIP-1g = macrophage inflammatory protein 1g; IL-9 = interleukin 9; IL-1b = interleukin 1 beta; IL-8Rb = interleukin 8 receptor b; C-10 = chemokine 10; CCR-1 = chemokine receptor 1; MIP-3a = macrophage inflammatory protein 3 alpha; CCR-2 = chemokine receptor 2.