Table 2.
Metabolic data at fasting state, at rest and during 18F-labelled FTHA PET scanning
| Less active | More active | Diff.* (95% CI) | P | |
|---|---|---|---|---|
| Total cholesterol (mmol l−1) | 3.99 ± 0.58 | 3.97 ± 0.58 | −0.02 (−0.28, 0.24) | 0.85 |
| HDL cholesterol (mmol l−1) | 1.19 ± 0.15 | 1.30 ± 0.17 | 0.10 (0.00, 0.20) | 0.04 |
| LDL cholesterol (mmol l−1) | 2.40 ± 0.63 | 2.32 ± 0.56 | −0.08 (−0.38, 0.22) | 0.56 |
| Triglyceride (mmol l−1) | 0.89 ± 0.51 | 0.78 ± 0.18 | −0.11 (−0.43, 0.21) | 0.60 |
| Before PET scanning | ||||
| Insulin (mU l−1) | 7.44 ± 4.98 | 6.56 ± 3.97 | −0.89 (−1.87, 0.09) | 0.07 |
| Glucose (mmol l−1) | 5.78 ± 0.30 | 5.64 ± 0.28 | −0.14 (−0.30, 0.02) | 0.08 |
| FFA (mmol l−1) | 0.35 ± 0.13 | 0.27 ± 0.13 | −0.08 (−0.18, 0.03) | 0.12 |
| Lactate (mmol l−1) | 0.78 ± 0.29 | 0.73 ± 0.31 | −0.04 (−0.24, 0.15) | 0.61 |
| Skeletal muscle PET scanning | ||||
| FFA (mmol l−1) | 0.42 ± 0.25 | 0.32 ± 0.23 | −0.11 (−0.30, 0.09) | 0.30 |
| Lactate (mmol l−1) | 0.58 ± 0.20 | 0.59 ± 0.25 | 0.06 (−0.29, 0.18) | 0.88 |
| Myocardial and hepatic PET scanning | ||||
| FFA (mmol l−1) | 0.44 ± 0.24 | 0.33 ± 0.24 | −0.11 (−0.30, 0.09) | 0.20 |
| Lactate (mmol l−1) | 0.56 ± 0.17 | 0.54 ± 0.14 | − 0.01 (− 0.13, 0.11) | 0.83 |
Values are means ±s.d. FTHA, 6-thia-hepta-decanoic acid; PET, positron emission tomography; CI, confidence interval for average difference in absolute values
*
Diff., average difference in absolute values between brothers; FFA, serum free fatty acid concentration; P, P value for difference between groups (paired t test).