Figure 5. Macrophage depletion affects the proliferation and differentiation of satellite cells during soleus muscle reloading following hindlimb suspension.

A, the number of satellite cells in macrophage-depleted soleus muscle is significantly greater than in non-depleted muscle at 2 days of reloading. B, MyoD-positive satellite cells decrease during the interval between 2 and 4 days of reloading in non-depleted but not in macrophage-depleted soleus muscles. *Significantly different from control at P < 0.05; #significantly different from treatment-matched 2 day sample at P < 0.05.