Figure 5. Membrane potential of submandibular acinar cells from wild-type and K_Ca3.1-, K_Ca1.1- and double-null mice.

Cell were stimulated with 0.3 μm CCh with or without K⁺ channel blockers (with 1 μm paxillin, with 3 μm clotrimazole, or with 1 μm paxilline and 3 μm clotrimazole). A, membrane potential of a submandibular acinar cell from wild-type mice recorded in perforated-patch configuration. B–D, membrane potentials recorded in cells from K_Ca3.1-, K_Ca1.1- and double-null mice. E, time-averaged mean membrane potentials in cells from wild-type or mutant mice as indicated. *P < 0.05.