Figure 2. Properties of adenosine release.

A, graph summarizing how adenosine release varies with stimulation frequency (data from 4 slices). The number of stimuli was kept constant (100) and the stimulation frequency was varied between 2 and 80 Hz. The data are normalized to the concentration of adenosine detected at a stimulus frequency of 20 Hz. B, superimposed traces from an adenosine biosensor following 20, 100 and 160 stimuli. The stimulus frequency was kept constant at 20 Hz. The stimulation strength was between 3 and 8 V (A) and 5 V (B).