Table 1.
PaO2 (mmHg) | PaCO2 (mmHg) | pH | ||
---|---|---|---|---|
Group 1 | Normoxia | 81.9 ± 3.2 | 38.4 ± 1.4 | 7.422 ± 0.013 |
Hypoxia | 27.9 ± 1.0*** | 22.9 ± 1.3*** | 7.542 ± 0.014*** | |
Normoxia + yohimbine | 93.3 ± 4.0 | 36.4 ± 2.2 | 7.428 ± 0.014 | |
Hypoxia + yohimbine | 32.0 ± 1.8*** | 23.7 ± 1.8*** | 7.496 ± 0.035 | |
Group 2 | Normoxia | 86.3 ± 4.1 | 39.3 ± 1.8 | 7.367 ± 0.023 |
Hypoxia | 34 ± 1.3*** | 27.6 ± 1.1*** | 7.451 ± 0.015*** | |
Normoxia + BIBP 3226 | 88.2 ± 3.1 | 38.2 ± 2.1 | 7.372 ± 0.031 | |
Hypoxia + BIBP 3226 | 33.7 ± 1.6*** | 28.1 ± 1.3*** | 7.446 ± 0.012*** |
Values are mean ± s.e.m. Normoxia (air breathing) and hypoxia (breathing 8% O2) in the absence or presence of either yohimbine or BIBP 3226. Asterisks indicate statistical significance of P < 0.001 (***) compared to normoxia.