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. 2007 May 31;582(Pt 3):1303–1316. doi: 10.1113/jphysiol.2007.127639

Figure 6. Lysyl oxidase, MMP-2, TIMP-1 and TIMP-2 mRNA.

Figure 6

Lysyl oxidase, MMP-2, TIMP-1 and TIMP-2 mRNA normalized to tissue weight, presented as fold changes relative to the mean of all control values, in Achilles tendon (A, C, E and G) and gastrocnemius muscle (B, D, F and H) subjected to concentric (CON), eccentric (ECC) and isometric (ISO) training (grey bars) versus contralateral controls (white bars). Values are geometric means ±s.e.m.A and B, LOX mRNA levels increased in tendon and muscle in response to all training types, though this only tended to be significant for CON trained muscle (†P = 0.06, ***P < 0.001). C, tendon MMP-2 mRNA increased after CON and ISO and tended to do so after ECC (†P = 0.1, *P < 0.05 **P < 0.01). D, ECC and ISO (and possibly CON) loading-induced MMP-2 mRNA expression in muscle (†P = 0.09, **P < 0.01, ***P < 0.001). E–H, TIMP-1 and TIMP-2 mRNA levels were increased in both tendon and muscle in response to all training types (P < 0.05) and in muscle tissue the effect of eccentric training was greater than concentric (P < 0.05).