Table 1.
Changes in nerve activity after raphé muscimol or vehicle injection
Raphé-muscimol | Before injection | After injection | Subsequent cooling | |
---|---|---|---|---|
Tail SNA | n= 7 | 52 ± 10 | 19 ± 6* | 18 ± 6* |
Back skin CVC-type | n= 8 | 39 ± 22 | 1 ± 0.4* | 8 ± 8* |
Raphé-vehicle | Before injection | After injection | ||
Tail SNA | n= 5 | 52 ± 13 | 48 ± 12 | |
Back skin CVC-type | n= 6 | 42 ± 20 | 23 ± 10 |
Values shown are 1 min means of activity (10 s spike counts) ±s.e.m. Columns show values just before raphé injection, 4–5 min after the injection (just before subsequent cooling), and at the nadir of the second subsequent cooling episode (after muscimol injection).
Significant differences (P < 0.05) from activity before the injection. After muscimol injection, subsequent cooling caused no further significant change. Raphé-vehicle injections also caused no significant change.