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A and B, inside-out patch clamp records from oocytes expressing Kir6.2ΔC36 (A) or SUR2A + Kir6.2 (B) illustrating the effect of application of 10 μm Rho123 in the presence of 2 mm ATP on channel activity in nucleotide-free solutions. C, average currents in nucleotide-free conditions for Kir6.2 and SUR2A + Kir6.2 channels measured before (grey bars) and after (black bars) application of 10 μm Rho123 in the presence of 2 mm ATP.
