Figure 3. Evaluating whether mGluRs act via K⁺ channels.

A, inspiratory bursts were transformed into inspiratory plateau potentials by intracellular Cs⁺, which blocks the attenuating effects of LY367385 (LY; 15 μm). B, MPEP (10 μm) attenuates Cs⁺-induced inspiratory plateau potentials. In A and B, arrows indicate inspiratory bursts shown at high time resolution in the insets at right. Voltage calibration bars in the insets apply to all traces in A and B. Individual time calibration bars are illustrated for traces and insets. Baseline membrane potential was –60 mV.