Figure 2. Averaged diastolic (lower values) and peak systolic (upper values) force (left panel) and [Ca²⁺]_i (right panel) at different stimulation frequencies at 1 mmol l⁻¹ Ca²⁺ from control (n= 10) and failing (n= 10) right ventricular trabeculae.

In controls, systolic force and [Ca²⁺]_i increased with frequency, whereas in failing muscles, systolic force decreased and [Ca²⁺]_i increased with frequency. In both groups, diastolic force and diastolic [Ca²⁺]_i remained constant. Values are expressed as means ±s.e.m.*P < 0.05 versus control group.