Figure 10. Lack of K_ATP channel activity impaired intracellular Ca²⁺ regulation during fatigue in FDB single fibres at 37°C.

Representative Ca²⁺ traces from one control wild-type fibre (A), and fibres that remained intact but stop contracting (B), that partially supercontracted (C), and that fully supercontracted in the presence of 10 μm glibenclamide (D). Bottom traces show the entire ${\text{Ca}}_{\text{i}}^{2+}$ trace, top traces show individual Ca²⁺ transient at the indicated contraction number with the dashed lines representing the unstimulated ${\text{Ca}}_{\text{i}}^{2+}$ before fatigue.