Figure 6. Mechanically-evoked and spontaneous activity of serosal/mesenteric afferent fibres.

Examples of mechanical stimulation with a blunt probe (A) in colonic afferent fibres from control (a), inflamed (b) and recovered (c) preparations. Impulses evoked by a 1 s calibrated blunt probe (B) and mean peak instantaneous frequency of the probe response (C) showed no significant changes between colonic afferent fibres from control, inflamed or recovered preparations (P > 0.05, n = 9, one-way ANOVA with Dunnet's post hoc test). Spontaneous discharge in responsive fibres was not significantly altered in inflammation and recovery.